Quality Research Chemicals Shop

Microdosing 1P-LSD



  1. What Is 1P-LSD Microdosing?
  2. The Science of 1P-LSD Microdosing
  3. How Do You Microdose With 1P-LSD?
  4. Benefits and Risks
  5. FAQ

Disclaimer: 1P LSD is an illegal substance in some areas, and we don’t promote or condone the use of the substance where it’s against the law. But, we accept that prohibited drug use occurs, and believe that offering responsible harm reduction info is crucial to keeping people safe. For that reason, this blog post was created to ensure the security of people who opt to use this substance.


Microdosing is the action of consuming sub-par quantities of psychedelics – most commonly LSD or psilocybin mushrooms, but also replacements such as psilocybin truffles or 1P LSD.

Sub perceptual signifies the effects are subtle but may make a significant impact on your life. Usually, individuals integrate sub-par doses in their weekly routine. Microdosers regularly reports higher levels of creativity, more energy, increased focus, and improved relational skills. People microdose so as to treat depression or nervousness, with frequently remarkable results. Some enthusiasts additionally report microdosing can help to heighten spiritual consciousness and enhance each of five senses. THE HISTORY OF MICRODOSING. Whilst the modern history of psychedelics reaches back into the 50s, interest in microdosing watched a significant revitalization with the publishing of Dr. James Fadiman’s guide to psychedelic exploration: safe, therapeutic and sacred journeys at 2011.

Dr Fadiman’s book explores microdosing as a subculture of psychedelic use. Even though a number of native cultures, as well as modern professionals, have used microdosing as a means to unlock a host of benefits. Fadiman’s book officially introduced the term microdosing, into the psychedelic mainstream. However. Fadiman’s book did not only contribute a part of terminology, it hastens the curiosity and imagination of millions of individuals fascinated with the reports of experienced microdosers. Additionally, it provided a host of practical info for anybody that wanted to give it a go, much of that has been incorporated into this program.

Dr. Fadiman’s ongoing research on micro-pain serves as one of the very some modern studies on the effects of microdosing especially. After the publication of The Psychedelic Explorer’s Guide, the Upcoming major increase from the people’s sense of microdosing came out of a podcast interview Dr. Fadiman gave with Tim Ferriss at March of 2015. Ferriss, who rose to fame after authoring the bestseller The Four Hour Work Week, has a huge audience of people interested in entrepreneurship, biohacking, self-experimentation, psychology, spirituality, along with a range of additional subject matters that will predispose them to an interest in the advantages of microdosing.

His podcast interview with Dr. Fadiman blasted the main messages about microdosing contained from The Psychedelic Explorer’s Guide out of a soapbox loudly enough to greatly increase a basic consciousness of the concept. Right after its atmosphere date, listeners of the Ferriss podcast weren’t just starting to experiment with microdosing on their very own, they were discussing it and sharing their fascination with their very own personal networks. Consequently, journalists started writing articles about microdosing, leading to even higher awareness and interest.

The Latest Source of fascination with microdosing comes from Ayelet Waldman’s book A Really Great Day: How Microdosing Made a Superb Difference in My Life, My Marriage, and my Mood. Waldman’s book discusses her 30 day protocol of microdosing with LSD to address a number of symptoms mainly caused by hormonal changes associated with menopause. Prior to microdosing, Waldman’s mood swings had become so intense as to place her marriage and her relationship with her kids at risk. Following that, in an interview with The Third Wave, she said, This month altered my entire life, and I’m sad every day that I cannot continue doing it lawfully.

Tens of thousands of individuals around the world are being turned on to microdosing – whether it is for treating health issues, fostering imagination, or giving entrepreneurs directions.


While psychedelic materials have been prohibited and prohibited from study from the majority of nations up till the past few years, lots of the world’s top specialists have made amazing strides picking on research started from the 50s and 60s. Although no research has been done on microdosing especially, we know something about what big doses of psychedelics do into the mind. Much of what we understand about how psychedelics work entails serotonin, a chemical that keeps our brain ticking.

It’s among the most crucial neurotransmitters in the brain and influences virtually everything we do, the way we believe to the way we process information. Classic psychedelics like LSD and Psilocybin share a comparable structure to serotonin, and works along a similar pathway&hellip. Many antidepressants try to make serotonin more abundant from the mind to make you feel better. Psychedelics work more directly, by mimicking serotonin. This usually implies that one of their most important effects would be to stimulate the serotonin receptor, found in the prefrontal cortex, known as HT2A. HT2A receptor stimulation leads to two outcomes: The creation of Brain-Derived Neurotrophic Factor. BDNF is like Miracle Gro for your mind. It stimulates growth, relations, and action.

1P LSD is subjectively comparable at LSD as well, with lots of users finding the ramifications to be practically the same. Chemically, the only difference between the two is that 1P LSD has a little propionyl group bonded to the 1 position of LSD’s indole ring.

It is possible that an extremely active DMN makes us to ruminate, over examine ourself, and step from the present moment to continuously question the past and the future. This helps you explain why these substances can be utilized to fight depression and stress, and also lead to insights and creative perspectives which otherwise remain inaccessible to people.

A flow state has been, undergone by all, at some stage in our own lives. The surfer the therapist absolutely in sync with her client, the salesman working the room in an out of body experience&hellip are samples of individuals acting at their best while at flow. In other words, stream is one of the wonderful adventures of being human. We’ve got no specific, non anecdotal evidence to suggest that microdoses of psychedelics can cause stream states – but we know that doses may alter the use of the brain in ways seen from the transition to a quite comparable seen from the transition to a leak state.

This is crucial for permitting flow states to occur. Since we know that moderate doses of psychedelics can cause comparable effects to a leak probably that a regular mircodosing regime will begin to appears to change our consciousness in the direction of flow.


Microdosing is the act of taking “sub-perceptual” doses of psychedelics, meaning the dose level is not high enough to cause substantial deviations from reality.

1P-LSD itself is possibly less potent than LSD – delivering just 38% of its cousin’s strength, according to testing on mice. However, this may not be a reliable indicator of 1P-LSD’s strength in humans, and many people report that 1P-LSD and LSD have similar subjective strength.

In practice, you may need to take slightly more 1P-LSD than LSD for the same effects. Hence one user, citing personal correspondence with Jim Fadiman, recommends a starting dose of 15 micrograms (as opposed to 10). This can then be adjusted up or down as required to reach your own ‘sub-perceptual’ level.

Like LSD, 1P-LSD is most commonly available on blotter paper, with each square tab typically containing 100-125 micrograms. Less common preparations include powder, pellets, or liquid suspensions.

When microdosing with 1P-LSD on blotter paper, there are two methods to prepare a microdose: cutting or volumetric.

The cutting method is exactly what it sounds like: cutting the blotter paper with an Exacto knife or scissors.

One drawback to this method is a potential lack of precision arising during the process of ‘laying’ the 1P-LSD – whereby a liquid suspension is applied across a sheet of blotter paper. If your 1P-LSD has somehow been laid unevenly, the cutting method will leave you with a degree of variation between microdoses that could otherwise be avoided.

The volumetric method is often preferable, since it helps to get around any variation in how a tab is laid or cut. This method involves submerging a full tab into distilled water or alcohol and taking small, measured quantities of the solution in a syringe to microdose. Volumetric microdosing requires some calculations and careful measurements, but will generally give a more accurate, consistent dose.

For the standard volumetric method, all you need to do is drop a 100 microgram tab into 10ml of distilled water or vodka, and leave it for a day or so in the dark. With these figures, 1ml of the solution should contain a reliable 10 microgram dose of 1P-LSD. And you can store this solution in the fridge for several months, as long as the container is sterile.

Read our full guide on volumetric measuring to learn more.

There is some disagreement in the microdosing community over whether it’s necessary to remove the tab after soaking. Some people find it attracts mold (if using distilled water), while others have even suggested the tabs might leach 1P-LSD back out of the solution, affecting the concentration of each dose.

In any case, a more controlled method of preparation would be to split your distilled water or vodka into thirds and soak your tab for three hours in each, decanting them into a sterile bottle for storage and finally disposing of the paper tab entirely.


Dr. James Fadiman, the author of the Psychedelic Explorer’s Guide, recommends taking a microdose once every three days.

Take a microdose on Day 1. Then do NOT take a microdose on Day 2 or Day 3.

Then, take another microdose on Day 4.

Observe the effects through this procedure by taking notes in a diary every day.

Continue the process of microdosing two times per week for several weeks. Take notes through the whole procedure on both the short-term, in-the-moment effects, and long-term changes in your mood, energy, and social behaviour.

Follow your regular routine while microdosing. You should not alter what you do. The purpose is to enhance your day-to-day existence by incorporating microdoses into your routine.

Whenever you try microdosing for the very first time, take a day off from work and social responsibilities. It’s going give you a possibility to observe and detect some effects before microdosing in a situation.

Be vigilant in observing the effects of microdosing on the 2 days between microdoses. A lot of people perceive increased emotions of flow, imagination, and energy the day after they microdose, and also the day of microdosing.

Microdosing 1P-LSD every day is not suggested. Psychedelics like 1P-LSD generate a tolerance, even with microdoses, which means you may see diminishing returns following a few days. This is the reason Dr. Fadiman suggested leaving a day or two between each dose.

Concern for your health is one more reason to avoid microdosing every day. There’s a heart risk of taking too many psychedelics over a lengthy amount of time. Though we don’t know exactly how this contrasts with regards to microdosing, it’s best to err on the side of caution, and avoid microdosing too frequently, or for over a few months at a time.

One other downside to microdosing every day is normalizing a very potent chemical. You may compare it to the use of coffee for productivity purposes. Whenever you drink coffee every day, with time you need to increase the dose to get the same effect. One cup of coffee turns into two or 3 or 4 cups of coffee within 2-3 months.

It’s best to leverage microdosing as an occasional advantage, as opposed to a consistent go-to like coffee.

Boost your microdosing campaigns


Whilst it’s an oversimplification, individuals typically microdose for two distinct reasons: to decrease the frequency and intensity of undesirable states or to improve the frequency and intensity of desirable mental states.

1: To reduce the frequency and intensity of undesirable states caused by various kinds of “mental disorder”, including:

Stress (i.e. Generalized or Social)
Mood disorders

To increase the frequency and strength of states/outcomes that are desirable:

Flow states
Improved relationships/increased compassion
Athletic coordination
Leadership development

We’re not fond of the term “Emotional Illness” because it pathologizes what’s frequently a part of one’s natural progression towards a much coherent, actualized self.

But for those struggling with depression, anxiety, Posttraumatic stress disorder, ADD/ADHD, mood disorders or addiction (to mention a few), microdosing may create a number of positive changes.

Given the tremendous safety record of LSD, microdosing 1P-LSD – especially with such small amounts – appears to be a safe and measurable way to explore the incredible possibilities that psychedelics have to offer.

As can be seen by the below chart comparing the relative harms of common substances, LSD is one of the safest substances you can find, biochemically and socially speaking. It’s much safer than alcohol!

Having said that, psychedelics are powerful substances and even microdoses have a risk potential.

Emotional turbulence or anxiety is possible while microdosing, largely due to psychedelics’ ‘amplifying effect’. LSD, for instance, tends to amplify your current mood, rather than act as a stimulant or numbing agent. For this reason, it is important to assess your mindset before consuming a microdose of 1P-LSD.

Since, like LSD, 1P-LSD has the potential to amplify your current mental state, we recommend discussing the risks with your physician if you suffer from psychosis, schizophrenia or severe anxiety, before you decide to begin microdosing. When overdone, microdosing can lead to manic states, which could exacerbate underlying conditions.

Since there is no clinical research on the safety of microdosing 1P-LSD, it’s best to avoid doing so for extended periods of time (longer than a few months). There is a potential heart risk associated with taking too many large doses of psychedelics over a long period of time – although we don’t know how this translates to microdosing.

Men and women are microdosing in an effort of self improvement or personal development. Reports indicate that microdosing can enhance creativity, productivity and energy, which may be used on the job or at other pursuits. The creative advantages of microdosing are connected to the enhancement of circulation conditions. Since microdosing lets you enter a flow state with more ease, this allows individuals to explore new and thrilling forms of consciousness. Click here to listen to our interview with entrepreneur Janet Chang, and hear the way she microdosed to enhance creativity and work performance. Countless people microdose to assist them resolve work related problems, produce new concepts, or just to decrease procrastination.

Microdosing may also help you out of the working environment, by enhancing your social interaction abilities, athletic performance and religious awareness. Getting the most out of microdosing is actually important – and based on the reason you are microdosing, you will need to prepare and incorporate appropriately. Our microdosing class will guide you throughout the numerous protocols to get the most out of microdosing, specific to your requirements. RISKS. By far the riskiest thing about microdosing is ordinarily the law – therefore it is vital check local rules before using 1P LSD. While not controlled in the USA, a case might be made which 1P LSD comes under the federal analogue law – at least when sold or owned for human consumption – as an analog of LSD.

Latvia is applied in by An identical amendment regarding derivatives. Nevertheless, in neither country have we heard about prosecutions for 1P LSD. And its origin remains unknown. Nevertheless, given anecdotal reports along with its compound likeness to LSD, the risks are comparable.


Can 1P LSD be detected in a drug test? . Given its cultural similarities to LSD, and its probably function as a prodrug of it1P LSD is likely to activate drug tests in the same manner. Nevertheless, LSD doesn’t to be included in standard drug tests and is only occasionally tested for in screens. Should you feel any other consequences, or your experience lasts considerably longer than 12 hours, then you might not have taken 1P LSD. In case your blotter paper had a taste, or numbed your tongue, it can have contained NBOMe or even DOx.

Note – if you’re using Ehrlich reagent to test your 1P LSD, then you may need to wait until half a hour to see a result, and it might be fainter than you are used to. It is since Ehrlich’s reagent binds to the same part of the molecule in which the propionyl class is, so it needs to compete for the same space. Is microdosing prohibited? . Microdosing isn’t necessarily prohibited. LSD 1P remains legal in several countries. See the risk section above for more details.

Is microdosing secure? . The most risky thing about microdosing is its character that is possibly illegal. Always be conscious of your regional laws and do not undertake any activities that are prohibited. There are no clinical studies of microdosing research in humans. Nevertheless, clinical trials for higher doses of LSD and psilocybin mushrooms also have shown that these substances are incredibly safe. What remains unknown is what impacts microdosing might have on the body. This is why we recommend microdosing for longer than a few months at a time.

One thing is for certain – with microdosing, there is no risk of having a “bad trip” or experiencing intense psychedelic effects. Taking a microdose is the ideal way to be introduced to psychedelics safely and comfortably.

How do I get started with microdosing?
There are lots of things to cover before you get started with microdosing – depending on the reasons you’re interested in the first place!

Upcoming legal changesRead more here
WordPress Appliance - Powered by TurnKey Linux